Webinar: Oral Colon Drug Delivery – Design Strategies

EIPG webinar

Next EIPG webinar is to be held on Wednesday 21st of February 2024 at 17.00 CET (16.00 GMT) in conjunction with PIER and University College Cork. Anastasia Foppoli, will discuss on the various approaches and the general aspects relevant to the design and technological features of colon drug delivery systems, for the local treatment of inflammatory bowel diseases the control of colonic bacterial growth and the improvement of the bioavailability of orally administered polypeptides and proteins.

Increasing interest is directed to delivery systems able to control the site of release. In this respect, colon drug delivery has been suggested for the local treatment of inflammatory bowel diseases, the control of colonic bacterial growth and the improvement of the bioavailability of orally administered polypeptides and proteins. Various approaches have been attempted including the use of prodrugs, coatings degraded by microflora enzymatic activity, and polymeric coatings which dissolve at specific pH. Another strategy relies on the exploitation of the relative constant small intestine transit time of pharmaceutical dosage forms. This talk includes the rational basis for various approaches, the general aspects relevant to the design and technological features of colon drug delivery systems, together with their classification and definition.

Anastasia Foppoli is Associate Professor at the School of Pharmacy, University of Milan.
After graduating in Chemistry and Pharmaceutical Technology at the University of Milan in 1998, she earned a PhD from the University of Cagliari. In 1999, she attended the School of Pharmacy of the University of Minnesota as a visiting scientist, dealing with the study of solid-state properties of drugs and excipients. She is the author of more than 60 publications, including research papers, reviews, book chapters and patents in the drug delivery area, and presented numerous lectures at national and international conferences. Her current research interests, within GazzaLaB Research group, concern the design and preparation of conventional as well as modified release oral dosage forms. She serves on the Editorial Advisory Board of Journal of Pharmaceutical Sciences (Elsevier, Amsterdam, NL) and Pharmaceutics (MDPI, Basel, CH), and is peer reviewer for several major journals in the field of pharmaceutical technology. She is member of SITELF, SCI, CRS Italy Local Chapter and AFI.

By the end of this webinar, you will be able to:

1. Understand the rational for colon delivery.
2. Define the various physiological determinants to the design of colon delivery systems.
3. Compare the different approaches proposed, criticalities and limitations.
4. Be informed on well-established and emerging technologies involved in the manufacturing of colon delivery systems.
5. Recognize the possible regulatory impact of colon delivery systems

Please register by filling out the Registration Form. Keep a record of the streaming details of the event that will be shown on your screen at the time of your registration.